Value of comparative genomic hybridization and fluorescence in situ hybridization for molecular diagnostics in multiple myeloma
نویسندگان
چکیده
منابع مشابه
The value of fluorescence in situ hybridization for the detection of 11q in multiple myeloma.
BACKGROUND AND OBJECTIVES A large number of chromosomal abnormalities have been detected in multiple myeloma (MM). The most frequent are chromosome 13q deletions and translocations affecting the immunoglobulin heavy chain gene (IGH). Recent studies using comparative genomic hybridization (CGH) have shown that gains of 11q represent one of the most frequent genomic changes in MM. However CGH is ...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2003
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2003.04417.x